why does cord blood contain hematopoietic stem cells

+ + + + + + + What is Cord Blood? After a baby is born and the umbilical cord is cut, some blood remains in the blood vessels of the placenta and the portion of the umbilical cord that remains attached to it. After birth, the baby no longer needs this extra blood. This blood is called placental blood or umbilical cord blood: cord blood for short. Cord blood contains all the normal elements of blood - red blood cells, white blood cells, platelets and plasma. But it is also rich in hematopoietic (blood-forming) stem cells, similar to those found in bone marrow.


This is why cord blood can be used for transplantation as an alternative to bone marrow. Cord blood is being used increasingly on an experimental basis as a source of stem cells, as an alternative to bone marrow. Most cord blood transplants have been performed in patients with blood and immune system diseases. Cord Blood transplants have also been performed for patients with genetic or metabolic diseases. More than 80 different diseases have been treated to date with unrelated cord blood transplants. [
Scientists are investigating the possibility that stem cells in cord blood may be able to replace cells of other tissues such as nerve or heart cells.


Whether cord blood can be used to treat other kinds of diseases will be learned from this research. Although umbilical cord blood transplants and infusions were initially used to treat hematologic cancers and bone marrow failures, more recently they have been applied to treatment of a wide range of disorders, encompassing hemoglobinopathies, such as thalassemia; hematologic cancer, such as acute myeloblastic leukemia, chronic myeloid leukemia, and non-Hodgkins lymphoma; immune deficiencies, such as severe combined immunodeficiency; and metabolic and genetic disorders, such as Hurler syndrome and Tay-Sachs disease. , Today, there are nearly 80 diseases that have been treated using these cells and research continues to develop new applications for cord blood in the field of regenerative medicine.


Currently, emerging research is ongoing through phase I and phase II clinical trials for diseases such as Cerebral Palsy and Type 1 Diabetes. ,

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